Nicotinamide Supplementation Improves Oocyte Quality and Offspring Development by Modulating Mitochondrial Function in an Aged Caenorhabditis elegans Model

Aging is associated with a decline in the quality of biological functions.Among the aging processes, reproductive aging is a critical process because of its intergenerational effects.However, the mechanisms underlying reproductive aging remain largely unknown.Female reproductive aging is the primary reason for limited fertility in mammals.Therefore

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Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice

Abstract Background During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive.The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be temporarily implanted over major vessels e.g.at the groin of the patient to bridge cardiogenic shock.To perform this procedure in

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